Background: The total mortality rate of COVID-19 is estimated almost at 2 % based on a wide range of publications. To avoid negative global impact of this new emergency, the entailment of control measures for prevention is highly recommended. Unfortunately, Iran has been the manifestation of attention as one of the countries is struggling with this pandemic. Here we intend to report a unique case of 2019-nCoV infected patient with underlying diseases and one of the rare pulmonary manifestations of 2019-nCoV infection (pleural effusion) who has recovered and discharged.