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Dr. Sitamanikyam Saladi, Dr. T. Vithya, Dr. Shankar Prasad and Dr. Shobha
Rani Hiremath
Department
of Pharmacy Practice, Al-Ameen College of Pharmacy, Bengaluru – 560027,
Karnataka, India
*Corresponding
author: Dr. Sitamanikyam Saladi,
Department of Pharmacy Practice, Al-Ameen College of Pharmacy, Bengaluru –
560027, Karnataka, India, Email: chikkireddisita@gmail.com
Citation: Dr. Sitamanikyam Saladi (2020) A Study on Prescribing Pattern of ANTIBIOTICS in Various Intensive Care Units of St. Philomena’s Hospital. Med Healthcare Rep, 2(2);1-4
Copyright: © 2020, Dr. Sitamanikyam Saladi, et al. This is an open-access article
distributed under the terms of the Creative Commons Attribution 4.0
International License, which permits unrestricted use, distribution and
reproduction in any medium, provided the original author and source are
credited.
ABSTRACT
INTRODUCTION:
Antibiotics are the class of drugs which are used to treat
microbial infections. Use of antibiotics has been major concern in various
intensive care units since it is most commonly used class of drug. The resistance developed due to the irrational use of
antibiotics is a global public health problem. OBJECTIVES: To
study the prescribing pattern of antibiotics in various Intensive care units of
St. Philomena’s hospital. METHODOLOGY: The study was conducted for a
period of 6 months. Data of patients admitted to various Intensive care units
of the hospital who fitted the inclusion criteria were collected and subjected
for evaluation. RESULTS: During the study period of 6 months, a total of
163 patients who fulfilled the inclusion criteria were included in the study.
In our study, male patients 92(56.44%) were higher in number than female
patients 71(43.56%). Geriatric patients 85(52.15%) were more in number than
adolescents 78(47.85%). Among these majority of the patients 92(56.44%) were
admitted to MICU. In our study, most preferred antibiotics as empirical
therapy, Cephalosporins 61(18.54%)
were the highest prescribed antibiotics and Oxazolidinones 2(0.61%) were the least used drug.
In post-empirical therapy analysis, highest preferred antibiotics were
Lincosamides 42(19.09%) and Cefoperazone+sulbactam 1(0.45%) and Glycylcycline
1(0.45%) least used drugs. In this study, we observed that 98(60.12%) of
patients, antibiotics were escalated and 18(11.04%) of patient’s antibiotics
were de-escalated and 47(28.83%) of patients prescription no changes were
found. While monitoring prescriptions, it was observed that majority of the ADR
was induced by Levofloxacin and majority of the DDIs were caused by
Levofloxacin+Ondansetron. CONCLUSION: We conclude the study by stating
that culture sensitivity test was performed for majority of the study
population. Choice of antibiotics were based on subjective and objective
evidence post empirically though empirical choice was different. Adverse drug
reactions, medication errors and drug interactions observed were minimum in
number which clearly indicates that the choice of drugs were rational, and no
incidence of hospital acquired infection have been observed during the study period
which clearly indicates that infection control committee is performing at its
best.
KEYWORDS:
Intensive care unit, Antibiotics, Rationality
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