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Open Access

Molecular Detection of Trypanosoma evansi in Royal Bengal Tiger (Panthera tigristigris)

Shrikant Kowalli Nirupama Jaisingh, M Rout, V. Manjunatha, Umashankar KS, Shivashankar BP, Rathnamma 

Article Type: Case Report | Release date: 10 Apr 2024

Trypanosomiasis, widely known as sleeping sickness in humans and Nagana in animals, is a vector-borne disease caused by Trypanosoma species transmitted by tabanid flies. It significantly impacts a wide range of species including large elephants, buffaloes, giraffes, tigers, lions and leopards across various regions. 

Open Access

Moxidectin as a Neuromodulator, A Review

Gregory Klein Schneider, Eliane Maria Zanchet

Article Type: Review | Release date: 10 Apr 2024

Very little is known about the pathophysiology of mood and alcohol use disorders and their treatment is equally lackluster. Consequently, new molecular targets are often being explored. T

Open Access

Case Report: Esophageal Atresia with Congenital Esophageal Stenosis... 18 Years Later

 Bigliardi Román, Salcedo Roxana, Messere Gabriela, Oviedo Adriana, Reynoso Ricardo, Rizk Alejandro, Ortiz Gonzalo, Ditaranto Andrés and Varela Amanda

Article Type: Case Report | Release date: 10 Apr 2024

We present a patient with Esophageal Atresia (EA) type C and Congenital Esophageal Stenosis (CES) treated in our hospital since birth. The first years she required several dilations and was studied according to her evolution, presenting respiratory complications until she was 7 years old. 

Open Access

A Review of the Phase 3 MAESTRO Trials for Resmetirom in Metabolic Function Associated Fatty Liver Disease

 Bipneet Singh Niroshan Ranjan Waryaam Singh Jahnavi Ethakota Sakshi Bai Palak Grover Gurleen Kaur Nidhisri Sridhar Merritt Bern

Article Type: Theoretical Review | Release date: 01 Apr 2025

Non-Alcoholic Fatty Liver Disease (NAFLD), is the leading cause of chronic liver disease in the United States. It encompasses liver conditions characterized by fat accumulation without excessive alcohol consumption. Early symptoms such as fatigue and abdominal pain are nonspecific, leading to delayed diagnosis until severe complications arise. 

Open Access

Unilateral Proptosis in a Child: An Unusual Case of Orbital Hydatidosis

 S.Moujrid, A.CHafo,M.Loudghiri, W.Bijou, Y.Oukessou, S. Rouadi, R. Abada, M. Roubal, M.Mahtar

Article Type: Case Report | Release date: 13 Feb 2025

Hydatidosis, also known as echinococcosis, is a zoonotic disease caused by the larval stage of Echinococcus granulosus, a parasite with a cosmopolitan distribution. Orbital involvement is exceedingly rare, with a reported incidence ranging from 0.3% to 1.0% among patients with echinococcosis. 

Open Access

Aggressive Giant Cell Granuloma of the Ethmoid: Diagnostic Challenges and Management Strategies

 S. Moujrid, M. Rochdi, M. Loudghiri, W. Bijou, Y. Oukessou, S. Rouadi, R. Abada, M. Roubal and M. Mahtar*

Article Type: Case Report | Release date: 13 Mar 2025

Giant Cell Granuloma (GCG) is a rare, benign but locally aggressive tumor-like lesion that predominantly affects the maxilla and mandible. Its occurrence in the ethmoid bone is extremely rare, with only a few cases documented in the literature. Due to its unusual location, ethmoidal GCG can pose diagnostic challenges and may mimic other osteolytic lesions.

Open Access

Laparoscopic Handsewn Cystogastrostomy Technique

Monika Gupta - Consultant:Gastrointestinal,Hpb and Minimal Invasive Surgery,Manipal Hospital Jaipur, India

Article Type: Complimentary Research

Open Access

Combined Use of Buccal Fat Pad and Collagen Membrane in Reconstruction of Surgical Defects of Buccal Muscosa: A Case Series

 Geeta Singh, Rangeet Bhadra, Kipa Guma and Jyotika Rajawat

Article Type: Case Report | Release date: 09 Mar 2025

Leukoplakia, verrucous hyperplasia, epithelial hyperplasia, erythroleukoplakia, mild to severe epithelial dysplasia, lichen planus, and squamous papillomas are examples of epithelial lesions of the oral cavity.

Open Access

Multiple Sclerosis Variants Case Series and Literature Review

 Heba Elmetwally Farahat, Mohammed Gamal Eldeen Sally and Abeer Ali Ateya

Article Type: Case Series | Release date: 28 Feb 2025

 Marburg type, Balo's concentric sclerosis and tumefactive MS represent special variants of multiple sclerosis, with a clinical picture characterized by clinically severe, quickly changing symptoms; also involving unusual neuron pathologic changes. Marburg type often features giant tumor liked demyelination plaques for example.

Open Access

Case Report: Esophageal Atresia with Congenital Esophageal Stenosis... 18 Years Later

 Bigliardi Román, Salcedo Roxana, Messere Gabriela, Oviedo Adriana, Rizk Alejandro, Ortiz Gonzalo, Ditaranto Andrés and Varela Amanda

Article Type: Case Report | Release date: 17 Feb 2024

We present a patient with Esophageal Atresia (EA) type C and Congenital Esophageal Stenosis (CES) treated in our hospital since birth. The first years she required several dilations and was studied according to her evolution,

Open Access

Unraveling Hepatic Pecomas: A 13-Years “Light” Systematic Review and Two New Case Reports.

 Pelizzo Patrizia, Dalla Bona Enrico, Romano Maurizio, Finotti Michele, Iacomino Alessandro, Grossi Ugo, Santoro Giulio A, Sergi Filomena D, Cester Mario, Presot Nicoletta V and Zanus Giacomo

Article Type: Review Article | Release date: 17 Feb 2025

Hepatic perivascular epithelioid cell tumors (PEComas) are rare mesenchymal neoplasms, first recognized in the early 1990s, char acterized by distinctive immunohistochemical markers such as HMB-45, SMA, and Melan-A. T

Open Access

The Role of Radiofrequency (RF) Energy in Transsphenoidal Surgery for Pituitary Adenomas

Mihit Kalawatia* and Ishita Bagadia

Article Type: Short Communication | Release date: 20 Feb 2025

The use of Radiofrequency (RF) energy in transsphenoidal surgery for pituitary adenomas offers a novel approach to simplify tumour resection and reduce risks.

Open Access

Revolutionising Our Approach Towards Aggressive Pituitary Adenomas Using Exosome - Based Liquid Biopsy

Mihit Kalawatia and Vaishnavi Parde

Article Type: Short Communication | Release date: 29 Jan 2025

Exosome-mediated liquid biopsy presents a revolutionary, non-in vasive technique for the early identification and management of aggressive pituitary adenomas. Unlike conventional diagnostic techniques.

Open Access

Benign Metastasizing Leiomyomas (Bml) An Imaging and Histological Challenge: A Case Report of Pelvic Extended Localization

Rosaria Meucci, Prof. Francesco Garaci, Erica Giacobbi, Manuel Scimeca, Cecilia Cerimele, Francesca Montesanto, Flavia Rufi, Carolina Goffredo, Maria Volpe, Prof. Lodovico Patrizi, Barbara Borelli, Colleen P. Ryan, Guglielmo Manenti

Article Type: Case Series | Release date: 31 Dec 2024

1. AbstractLeiomyomas are the most common gynecological tumors; they are benign and originate from smooth muscle cells together with fibrous connective tissue. The most common location is the uterus although rare cases of extra-uterine locations with benign histo- logical features have been described, such as intravenous leiomyo- matosis, disseminated peritoneal leiomyomatosis, benign metasta- sizing leiomyomas, 

Open Access

Goldenhar Syndrome: Morphological appearance

Salahiddine Saghir, Houda Bella, Rachid Abilkassem, Abdelhakim Ourrai, Amal Hassani¹ and Aomar Agadr

Article Type: Clinical Image | Release date: 16 Dec 2024

A 14-day-old newborn, born after a monitored pregnancy carried out until 39 weeks of gestation, presents with facial dysmorphia (Figure 1) characterized by right hemifacial hypoplasia and pre-au ricular diverticula. Orbital-cerebral imaging revealed left-sided fa cial asymmetry, hypoplasia of the malar bone, cheek soft tissues, nasal fossae, and agenesis of the corpus callosum. Additionally, general assessment did not reveal any cardiac, vertebral, or renal malformations. The diagnosis of Goldenhar Syndrome was con f irmed through molecular biology.

Open Access

Congenital Genu Recurvatum: An Infrequent Clinical Finding in the Delivery Room

 Houda Bella, Salahiddine Saghir, Rachid Abilkassem, Abdelhakim Ourrai, Amal Hassani and Aomar Agadr

Article Type: Clinical Image | Release date: 16 Dec 2024

 1. Clinical Image:A female newborn, born at term via vaginal delivery in a cephalic presentation, was examined at her first hour of life.

Open Access

Clinical Insights on Neonatal Teeth: Case Analysis and Complications

 Houda Bella, Salahiddine Saghir, Abdelhakim Ourrai, Amal Hassani and RachidAbilkassem

Article Type: Clinical Image | Release date: 16 Dec 2024

1. Clinical ImageA female newborn presented to the neonatology unit at Moham med V Military Instruction Hospital in Rabat on day 7 of life due to the presence of a neonatal tooth. Clinical examination revealed a single tooth located at the mandibular incisor area, with signifi cant mobility, which posed a potential risk for complications such as aspiration or oral injury. After careful evaluation, an extraction was performed under local anesthesia to prevent any risk of inha lation or traumatic ulceration.

Open Access

A Rare Cause of Persistent Constipation in Infants

 Houda Bella, Abdelillah Radi, Rachid Abilkasem, Abdelhakim Ourai, Amal Hassani and Aomar Agadr

Article Type: Clinical Image | Release date: 16 Dec 2024

A 9-month-old female with no prior medical history presented with persistent constipation that began at 3 months of age. Clinical examination revealed an infant with normal psychomotor development and age-appropriate growth parameters.

Open Access

Efficacy of Sulfadoxine Pyrimethamine as an Intermittent Preventive Treatment in Real-World Conditions on Parameters at Childbirth in Mali

Oumou Coulibaly, Mariam Tall, Abdou KB KAYENTAO, Mahamadou Dembele, Mahamadou Guindo, Sory I Diawara1 and Kassoum Kayentao

Article Type: Research Article | Release date: 28 Nov 2024

1. Abstract:Malaria during pregnancy is a major public health problem and is often associated with complications during pregnancy and childbirth. The aim of this study is to evaluate the effectiveness of intermittent preventive treatment with sulfadoxine pyrimethamine on delivery parameters.

Open Access

Therapeutic Algorithm for Duodenal Varices: A Case Series

Matsuda T, Ishikawa T, Sasaki R, Nishimura T, Iwamoto T, Takami T and Sakaida I

Article Type: Case Series | Release date: 29 Aug 2024

ABSTRACT Background: Duodenal varices cause fatal bleeding and are potentially life-threatening. Treatment guidelines for duodenal varices have not yet been established due to their low incidence. We report a case series of patients with duodenal varices admitted to our hospital between April 2012 and June 2017 and share our therapeutic algorithm for duodenal varices.

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